Install Dev Tools ~45 minutes Install Subversion. http://metissian.com/projects/macosx/subversion/ ~5 minutes The third-party install supports Intel Macs, so these two Boost steps can be skipped. Download Boost-jam http://sourceforge.net/project/showfiles.php?group_id=7586&package_id=72941 The PPC version seems to work on Intel Macs. Copy/link to /usr/local/bin ~5 minutes Download and install Boost 1.33.1 http://prdownloads.sourceforge.net/boost/boost_1_33_1.tar.gz?download 'sudo bjam "-sTOOLS=gcc" --prefix=/usr/local/boost_1_33_1-gcc4_0 install' ~45 minutes Download and install FFTW http://www.fftw.org ./configure;make;sudo make install <1 hour Blas and LibXML are already installed Check out third-party svn co svn+ssh://mplab.ucsd.edu/usr/local/svnroot/third-party Untar any desired packages (at least the Boost package) and install them. ~10 minutes Check out MPUtil svn co svn+ssh://mplab.ucsd.edu/usr/local/svnroot/MPUtil Check out FeatureLearning svn co svn+ssh://mplab.ucsd.edu/usr/local/svnroot/FeatureLearning/trunk FeatureLearning Check out CERT svn co svn+ssh://mplab.ucsd.edu/usr/local/svnroot/CERT/trunk CERT If Matlab is not installed on the machine you will also need to get all of the Kernel sources and the SVM weights files. Install CocoaSequenceGrabber Make sure the 'Installation Directory' build setting is set to '@executable_path/../Frameworks'. In the two Xcode projects a number of header and library search paths may need to be modified to point to the correct locations. Also make sure the architecture setting is set properly. If the svnversion executable is not available, delete or disable the shell script phase in the CERTFramework project. It can be installed via Fink.